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Stopping GLP-1 drugs? Don’t be surprised if weight rebounds Weight-loss drugs such as Ozempic, Mounjaro and Wegovy may lead to people losing weight, but a review of trials conducted on thousands of adults shows that many regain weight soon after they stop using the medication.  Weight-loss drug users, on average, regain weight at a rate of 0.4 kilograms per month after they stop taking their weight-loss medications, a review of 63 trials covering more than 9,000 individuals published in the British Medical Journal on Wednesday found.
Of these, around 6,000 were on GLP-1 drugs such as semaglutide or tirzepatide and had stopped taking them, while around 3,000 were on behavioural weight management programmes (BWMPs) that include a mix of counselling, diet, exercise and other support measures. Patients who went on the weight-loss drugs and then stopped them regained their entire baseline weight on average around 20 months after they stopped taking the drugs. "What the paper finds, very unsurprisingly, is that when you stop a drug that is prescribed to cause weight loss, then people begin to regain their weight," said Dr. Hertzel Gerstein, professor of medicine and endocrinologist at McMaster University. Read more about what happens to the body when a person stops taking the medications. 
Meat, cheese and whole grains: What new U.S. food guide wants Americans to eat The U.S. government wants Americans to "eat real food," dietary guidelines released on Wednesday said. "The new Guidelines deliver a clear, common-sense message to the American people: eat real food," the U.S. Department of Health and Human Services and Department of Agriculture said in a statement. Americans are being asked to avoid highly processed foods in general, including foods with added sugars and artificial additives. The 10-page document, released by Health and Human Services Secretary Robert F. Kennedy Jr. and Agriculture Secretary Brooke Rollins, asks Americans to prioritize protein consumption for every meal and consume full-fat dairy with no added sugars. While the document says Americans should "prioritize oils with essential fatty acids, such as olive oil," it adds that other options "can include butter or beef tallow." Read more about the recommendations and age-specific advice for children. 
— THE TOPIC — Why doctor’s say it’s not too late for a flu shot Infectious disease doctors describe this year’s flu season so far as a shorter, sharper spike, driven primarily by the H3N2 strain of the virus. “My best bet is that this will go down as one of the worst flu seasons that Canada has ever experienced,” said Dr. Fahad Razak, an internist at St. Michael’s Hospital in Toronto. Data suggests the peak of the flu season may have happened at the end of 2025, as Public Health Ontario numbers show the positivity rate declining. “I think the west is a little bit behind central Canada and the east, but certainly in Ontario and Quebec, the peak of influenza was the week before Christmas and the week of Christmas,” said infectious diseases physician Dr. Allison McGeer. But doctors say the ripple effect of the December surge is still being felt in hospitals. “Across Ontario, you’re seeing the examples of congestion and hospitals struggling to deal with the overflow of cases,” Razak said. “Hospitals can experience a 20, 30, 40 per cent surge in the number of patients who require admission during a few weeks during that surge of influenza cases and that is the tip-over event.” Dr. Kevin Wasko, chief of emergency medicine at North York General Hospital in Toronto, said that the admissions from those cases are still having an impact. “That is causing congestion in the emergency department and that is causing strain on the system,” Wasko said. Public health experts say the best time to get the flu shot is in the fall, before the season begins. But even now, there could be some benefit in getting a vaccine if you did not roll up your sleeves as another spike in cases could still happen. “What we have seen so far is the surge of influenza A, and some seasons, we also will see an outbreak of influenza B,” said Dr. Jeff Kwong, a public health and family physician. “They typically happen a bit later. And so that’s why if you haven’t gotten vaccinated yet, it still would be worthwhile to get vaccinated so that you are protected in case there is an influenza B wave that comes in the coming months.” | 
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